Blar i forfatter "Bøtker, Hans Erik"
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Effect of everolimus initiation and calcineurin inhibitor elimination on cardiac allograft vasculopathy in de novo heart transplant recipients - Three-Year results of a Scandinavian randomized trial
Arora, Satish; Andreassen, Arne K.; Karason, Kristjan; Gustafsson, Finn; Eiskjær, Hans; Bøtker, Hans Erik; Rådegran, Göran; Gude, Einar; Ioanes, Dan; Solbu, Dag; Dellgren, Göran; Ueland, Thor; Aukrust, Pål; Gullestad, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)<i>Background</i>: Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation, and the effect of different immunosuppressive regimens on CAV is not fully understood. The randomized SCHEDULE trial (Scandinavian Heart Transplant Everolimus De Novo Study With Early Calcineurin Inhibitors Avoidance) evaluated whether initiation of the proliferation signal inhibitor ... -
ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
Madonna, Rosalinda; Van Laake, Linda W.; Bøtker, Hans Erik; Davidson, Sean M.; De Caterina, Raffaele; Engel, Felix B.; Eschenhagen, Thomas; Fernandez-Aviles, Francesco; Hausenloy, Derek J.; Hulot, Jean-Sebastien; Lecour, Sandrine; Leor, Jonathan; Menasché, Philippe; Pesce, Maurizio; Perrino, Cinzia; Prunier, Fabrice; Van Linthout, Sophie; Ytrehus, Kirsti; Zimmermann, Wolfram-Hubertus; Ferdinandy, Péter; Sluijter, Joost P.G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-17)Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit from novel therapeutic strategies, such as cellbased therapies. We recently discussed the therapeutic potential of cell-based therapies and provided recommendations on how to improve the therapeutic translation of these ... -
Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
Perrino, Cinzia; Ferdinandy, Péter; Bøtker, Hans Erik; Brundel, Bianca J. J. M; Collins, Peter; Davidson, Sean M; Den Ruijter, Hester M.; Engel, Felix B.; Gerdts, Eva; Girao, Henrique; Gyöngyösi, Mariann; Hausenloy, Derek J.; Lecour, Sandrine; Madonna, Rosalinda; Marber, Michael; Murphy, Elizabeth; Pesce, Maurizio; Regitz-Zagrosek, Vera; Sluijter, Joost P.G.; Steffens, Sabine; Gollmann-Tepeköylü, Can; Van Laake, Linda W.; Van Linthout, Sophie; Schulz, Rainer; Ytrehus, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and morbidity in both men and women. Sex, however, affects several aspects of IHD, including pathophysiology, incidence, clinical presentation, diagnosis as well as treatment and outcome. Several diseases or risk factors frequently associated with IHD can modify cellular signalling cascades, thus affecting ischaemia/reperfusion ...